Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Moderately Good
Based on 42 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Nattokinase (2,000 FU) (enzyme from Natto Extract) (Non-GMO soy derived)
100 mg
**

Top Medical Research Studies

8
Nattokinase shows mixed cholesterol benefits
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.

However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.

We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.

In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More

Most Useful Reviews

9
Supports heart health
30 people found this helpful
Nattokinase is an enzyme derived from fermented soy products and is known to dissolve excess fibrin and improve circulation, reducing clot risks. It also lowers bad LDL cholesterol while raising good HDL cholesterol, improves blood viscosity, and regulates blood pressure. Given the prevalence of cardiovascular diseases after age 55, this supplement is vital. I have been taking it for over four months and it has positively impacted my blood consistency.
Read More
9
Post-COVID recovery
15 people found this helpful
I highly recommend nattokinase—I am ordering it for the second time and share it with my family. This product has remarkable benefits. The prescribed dosage aids recovery post-COVID by thinning the blood, reducing fibrin, disinfecting, and normalising my blood pressure while lowering cholesterol levels. My leg swelling has decreased, and my overall well-being has improved thanks to this supplement. I take one capsule twice a day.
Read More
9
Improved well-being
11 people found this helpful
Nattokinase has been fantastic for my mother, who deals with hypertension and has a stroke history. This product effectively thins the blood, stopping clots from forming. My mother quickly noticed improvements—her dizziness and headaches diminished, and her blood pressure became stable. This is an outstanding result for her, and she feels healthier and more energetic!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
8
Nattokinase shows mixed cholesterol benefits
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.

However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.

We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.

In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 42 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Supports heart health
30 people found this helpful
Nattokinase is an enzyme derived from fermented soy products and is known to dissolve excess fibrin and improve circulation, reducing clot risks. It also lowers bad LDL cholesterol while raising good HDL cholesterol, improves blood viscosity, and regulates blood pressure. Given the prevalence of cardiovascular diseases after age 55, this supplement is vital. I have been taking it for over four months and it has positively impacted my blood consistency.
Read More
9
Post-COVID recovery
15 people found this helpful
I highly recommend nattokinase—I am ordering it for the second time and share it with my family. This product has remarkable benefits. The prescribed dosage aids recovery post-COVID by thinning the blood, reducing fibrin, disinfecting, and normalising my blood pressure while lowering cholesterol levels. My leg swelling has decreased, and my overall well-being has improved thanks to this supplement. I take one capsule twice a day.
Read More
9
Improved well-being
11 people found this helpful
Nattokinase has been fantastic for my mother, who deals with hypertension and has a stroke history. This product effectively thins the blood, stopping clots from forming. My mother quickly noticed improvements—her dizziness and headaches diminished, and her blood pressure became stable. This is an outstanding result for her, and she feels healthier and more energetic!
Read More
8
Significant cholesterol reduction
10 people found this helpful
Great product. Combined with Selenium and Vitamin C, it has gradually reduced my LDL cholesterol from 4.8 to 3.6 and total cholesterol from 7.3 to 5.9. My triglycerides have decreased from 1.7 to 1.0 over the past five months (official blood tests). I’m a very happy customer.
Read More
9
Enhanced blood flow
4 people found this helpful
Nattokinase has greatly improved my blood flow since my previous DVTPE treatment with Coumadin. It prevents platelet clumping and effectively stops clots from forming. I share my experience with everyone; the high price is worth it!
Read More

Frequently Asked Questions

8
Significant cholesterol reduction
10 people found this helpful
Great product. Combined with Selenium and Vitamin C, it has gradually reduced my LDL cholesterol from 4.8 to 3.6 and total cholesterol from 7.3 to 5.9. My triglycerides have decreased from 1.7 to 1.0 over the past five months (official blood tests). I’m a very happy customer.
7.5
Effective cholesterol remedy
10 people found this helpful
Worth trying if your cholesterol is unbalanced. Nattokinase regulates cholesterol levels, proving effective over three months, and doubling the dosage may help. Avoid statins at all costs; this is a much better option.
9
Effective for tinnitus
3 people found this helpful
I initially purchased nattokinase for my husband to manage his high cholesterol. To my surprise, it also helped with the noise in my right ear. On the fifth day of taking it, the noise disappeared. It’s important to take it early in the morning on an empty stomach, 40 minutes before meals, without mixing it with other supplements.
9
Cholesterol improvement
2 people found this helpful
My friend monitored their high cholesterol for almost half a year. After using the product, their cholesterol significantly improved. They encouraged me to try it, and I promptly bought two bottles to take with CoQ10 daily. I look forward to the benefits from this entirely natural health care product.
9
Improved well-being
11 people found this helpful
Nattokinase has been fantastic for my mother, who deals with hypertension and has a stroke history. This product effectively thins the blood, stopping clots from forming. My mother quickly noticed improvements—her dizziness and headaches diminished, and her blood pressure became stable. This is an outstanding result for her, and she feels healthier and more energetic!
9
Post-COVID recovery
15 people found this helpful
I highly recommend nattokinase—I am ordering it for the second time and share it with my family. This product has remarkable benefits. The prescribed dosage aids recovery post-COVID by thinning the blood, reducing fibrin, disinfecting, and normalising my blood pressure while lowering cholesterol levels. My leg swelling has decreased, and my overall well-being has improved thanks to this supplement. I take one capsule twice a day.
7.5
Improved circulatory system
6 people found this helpful
Good price! I've used this product for five years. I feel my circulatory system has improved, along with decreases in my blood pressure and cholesterol levels.
7.5
Significant improvement
1 people found this helpful
This product greatly aids in lowering high cholesterol. My friend tracked their cholesterol for about six months and noted significant improvement. I was persuaded to try it and purchased two bottles, taking one capsule daily alongside CoQ10, eager to see the positive effects of this pure natural health product.
7.5
Potential health benefits
36 people found this helpful
Nattokinase is an excellent blood thinner that dissolves clots in blood vessels. It supports healthy fibrinogen levels. Key benefits include reducing lymph viscosity, addressing increased blood clotting, lowering LDL cholesterol levels, and preventing coronary heart disease, strokes, and heart attacks. It also contributes to intestinal microflora normalisation and bone density, and aids skin healing. Importantly, avoid taking it with other blood thinning medications. I’ve observed improvements in my grandmother’s health—she feels better!
7.5
Supports normal blood density
1 people found this helpful
Nattokinase is an excellent blood thinner, necessary for high cholesterol and reducing the risk of stroke. I take one capsule daily to maintain normal blood density.
8
Nattokinase shows mixed cholesterol benefits
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.

However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
7
Nattokinase affects hemostatic factors
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.

We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.

In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.

References

  1. Liu X, Zeng X, Mahe J, Guo K, He P, et al. The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2023;15. doi:10.3390/nu15194239
  2. Yoo HJ, Kim M, Kim M, Lee A, Jin C, et al. The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects. Food Funct. 2019;10:2888. doi:10.1039/c8fo02324g
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