This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.
However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects.
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.
We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.
In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More
Most Useful Reviews
9
Supports heart health
30 people found this helpful
Nattokinase is an enzyme derived from fermented soy products and is known to dissolve excess fibrin and improve circulation, reducing clot risks. It also lowers bad LDL cholesterol while raising good HDL cholesterol, improves blood viscosity, and regulates blood pressure. Given the prevalence of cardiovascular diseases after age 55, this supplement is vital. I have been taking it for over four months and it has positively impacted my blood consistency.
Read More
9
Post-COVID recovery
15 people found this helpful
I highly recommend nattokinase—I am ordering it for the second time and share it with my family. This product has remarkable benefits. The prescribed dosage aids recovery post-COVID by thinning the blood, reducing fibrin, disinfecting, and normalising my blood pressure while lowering cholesterol levels. My leg swelling has decreased, and my overall well-being has improved thanks to this supplement. I take one capsule twice a day.
Read More
9
Improved well-being
11 people found this helpful
Nattokinase has been fantastic for my mother, who deals with hypertension and has a stroke history. This product effectively thins the blood, stopping clots from forming. My mother quickly noticed improvements—her dizziness and headaches diminished, and her blood pressure became stable. This is an outstanding result for her, and she feels healthier and more energetic!
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.
However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects.
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.
We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.
In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 42 Reviews
7.8
All Reviews
Positive Reviews
Negative Reviews
9
Supports heart health
30 people found this helpful
Nattokinase is an enzyme derived from fermented soy products and is known to dissolve excess fibrin and improve circulation, reducing clot risks. It also lowers bad LDL cholesterol while raising good HDL cholesterol, improves blood viscosity, and regulates blood pressure. Given the prevalence of cardiovascular diseases after age 55, this supplement is vital. I have been taking it for over four months and it has positively impacted my blood consistency.
Read More
9
Post-COVID recovery
15 people found this helpful
I highly recommend nattokinase—I am ordering it for the second time and share it with my family. This product has remarkable benefits. The prescribed dosage aids recovery post-COVID by thinning the blood, reducing fibrin, disinfecting, and normalising my blood pressure while lowering cholesterol levels. My leg swelling has decreased, and my overall well-being has improved thanks to this supplement. I take one capsule twice a day.
Read More
9
Improved well-being
11 people found this helpful
Nattokinase has been fantastic for my mother, who deals with hypertension and has a stroke history. This product effectively thins the blood, stopping clots from forming. My mother quickly noticed improvements—her dizziness and headaches diminished, and her blood pressure became stable. This is an outstanding result for her, and she feels healthier and more energetic!
Read More
8
Significant cholesterol reduction
10 people found this helpful
Great product. Combined with Selenium and Vitamin C, it has gradually reduced my LDL cholesterol from 4.8 to 3.6 and total cholesterol from 7.3 to 5.9. My triglycerides have decreased from 1.7 to 1.0 over the past five months (official blood tests). I’m a very happy customer.
Read More
9
Enhanced blood flow
4 people found this helpful
Nattokinase has greatly improved my blood flow since my previous DVTPE treatment with Coumadin. It prevents platelet clumping and effectively stops clots from forming. I share my experience with everyone; the high price is worth it!
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Nattokinase is an enzyme extracted from a traditional Japanese food called natto, which is made from fermented soybeans. This enzyme is thought to have potential health benefits, primarily for cardiovascular health. Nattokinase is believed to support the breakdown of fibrin in the blood, which can help improve circulation and reduce the risk of blood clot formation. As a dietary supplement, it is often marketed for its possible ability to promote healthy blood flow and cardiovascular function.
While some studies suggest that nattokinase may help reduce blood pressure and enhance overall heart health, research is still ongoing. As with any supplement, it is essential to consult with a healthcare professional before adding nattokinase to your regimen, especially if you are on blood-thinning medications or have underlying health conditions. Overall, while nattokinase might offer some intriguing health benefits, more comprehensive studies are needed to fully understand its efficacy and safety profile.
Based on user reviews, the time it typically takes to see results from taking nattokinase for high cholesterol varies. Many users report significant improvements in their cholesterol levels after a few months of consistent use. For instance, one user noted a steady reduction in LDL cholesterol and total cholesterol after five months of taking the supplement Read Review. Another user mentioned a noticeable effect on their cholesterol after three months Read Review.
Results can manifest fairly quickly for some; one reviewer observed a reduction in their cholesterol numbers just one week after starting Read Review. However, many users emphasize the importance of patience and consistency, suggesting a use period of between three to six months before fully assessing effectiveness for high cholesterol management Read Review. Overall, most users seem to agree that with regular intake, nattokinase shows its benefits over time.
This supplement, specifically nattokinase, has been studied for its potential benefits on cholesterol levels, but the results are mixed. One study involving 113 participants showed that after 120 days of using nattokinase supplements, there were significant reductions in total cholesterol and LDL cholesterol, suggesting some positive effects on dyslipidemia [1]. However, it’s worth noting that the same study found no significant changes in HDL cholesterol or triglycerides, indicating that while there may be some benefits, they are not comprehensive across all lipid profiles.
Another study with 100 participants further highlighted this point, showing that while nattokinase supplementation had some impact on hemostatic factors, it did not lead to significant improvements in overall cholesterol management [2]. Therefore, while there is some evidence that nattokinase can lower certain cholesterol levels, the data suggests it may not be a one-size-fits-all solution for managing high cholesterol effectively. Users should consult with healthcare professionals before incorporating such supplements into their regimen.
Users report a range of improvements in their health after incorporating nattokinase into their routines, particularly regarding cholesterol management, blood thickness, and overall cardiovascular health. Several individuals noted significant reductions in LDL cholesterol levels, with one user sharing a remarkable drop from 4.8 to 3.6 in five months Read Review. Others emphasized the supplement's role in stabilizing blood pressure and enhancing circulation, with many citing improvements in symptoms associated with hypertension and high cholesterol. A user even observed a decrease in dizziness and headaches in their family member, connecting this relief to nattokinase's ability to thin the blood Read Review.
Additionally, anecdotal evidence suggests that nattokinase may aid in recovery post-COVID, specifically in reducing leg swelling and improving overall well-being Read Review. Regular users, particularly those managing chronic conditions, seem to experience gradual but impactful changes, underscoring the enzyme's broad applicability for those seeking natural alternatives for circulatory health Read Review. However, as with any supplement, individual results can vary, and it is advised to maintain patience and consistency in usage to fully gauge its effectiveness.
Based on user reviews, many individuals have reported positive experiences when combining nattokinase with other supplements for managing high cholesterol. For example, one user noted significant reductions in both LDL and total cholesterol levels when using nattokinase alongside Selenium and Vitamin C, achieving a remarkable drop from 4.8 to 3.6 in LDL cholesterol over five months Read Review. Additionally, another reviewer mentioned taking nattokinase daily along with CoQ10, expressing optimism about the potential benefits this combination could provide in improving their overall health Read Review.
However, some users have cautioned against mixing nattokinase with other blood-thinning supplements, emphasizing the need for careful monitoring. One individual specifically advised avoiding other blood thinners when taking nattokinase, citing its effectiveness in managing blood viscosity Read Review. Others suggested the importance of timing and dosages, indicating that taking nattokinase on an empty stomach before meals can enhance its effects Read Review. While combinations with certain supplements seem beneficial, it's crucial for users to consult healthcare providers to ensure safety and maximize health outcomes.
Based on user reviews, there appears to be a consensus on the appropriate dosage of Nattokinase for managing high cholesterol. Many users recommend taking one capsule twice a day to effectively lower LDL cholesterol levels and improve overall cardiovascular health. For instance, one user noted they take one capsule in the morning on an empty stomach and experienced significant benefits, including a reduction in the noise in their ear and noticeable drops in cholesterol levels after regular use Read Review. Another user reiterated the effectiveness of taking one capsule daily, espousing its benefits in maintaining normal blood density and lowering cholesterol Read Review.
Additionally, users highlighted the importance of consistency and patience in observing changes. For example, one user shared that they meticulously tracked their cholesterol over six months and saw significant improvement, which they attributed to their regimen of taking nattokinase alongside CoQ10 daily Read Review. While the standard suggestion seems to hover around one to two capsules daily, some users mentioned that increasing dosage may be beneficial, hinting at the subjective nature of effective dosing based on individual response and health conditions Read Review. Overall, Nattokinase shows promise in managing cholesterol levels with a typically recommended dosage of one capsule daily, subject to personal health needs.
8
Significant cholesterol reduction
10 people found this helpful
Great product. Combined with Selenium and Vitamin C, it has gradually reduced my LDL cholesterol from 4.8 to 3.6 and total cholesterol from 7.3 to 5.9. My triglycerides have decreased from 1.7 to 1.0 over the past five months (official blood tests). I’m a very happy customer.
7.5
Effective cholesterol remedy
10 people found this helpful
Worth trying if your cholesterol is unbalanced. Nattokinase regulates cholesterol levels, proving effective over three months, and doubling the dosage may help. Avoid statins at all costs; this is a much better option.
9
Effective for tinnitus
3 people found this helpful
I initially purchased nattokinase for my husband to manage his high cholesterol. To my surprise, it also helped with the noise in my right ear. On the fifth day of taking it, the noise disappeared. It’s important to take it early in the morning on an empty stomach, 40 minutes before meals, without mixing it with other supplements.
9
Cholesterol improvement
2 people found this helpful
My friend monitored their high cholesterol for almost half a year. After using the product, their cholesterol significantly improved. They encouraged me to try it, and I promptly bought two bottles to take with CoQ10 daily. I look forward to the benefits from this entirely natural health care product.
9
Improved well-being
11 people found this helpful
Nattokinase has been fantastic for my mother, who deals with hypertension and has a stroke history. This product effectively thins the blood, stopping clots from forming. My mother quickly noticed improvements—her dizziness and headaches diminished, and her blood pressure became stable. This is an outstanding result for her, and she feels healthier and more energetic!
9
Post-COVID recovery
15 people found this helpful
I highly recommend nattokinase—I am ordering it for the second time and share it with my family. This product has remarkable benefits. The prescribed dosage aids recovery post-COVID by thinning the blood, reducing fibrin, disinfecting, and normalising my blood pressure while lowering cholesterol levels. My leg swelling has decreased, and my overall well-being has improved thanks to this supplement. I take one capsule twice a day.
7.5
Improved circulatory system
6 people found this helpful
Good price! I've used this product for five years. I feel my circulatory system has improved, along with decreases in my blood pressure and cholesterol levels.
7.5
Significant improvement
1 people found this helpful
This product greatly aids in lowering high cholesterol. My friend tracked their cholesterol for about six months and noted significant improvement. I was persuaded to try it and purchased two bottles, taking one capsule daily alongside CoQ10, eager to see the positive effects of this pure natural health product.
7.5
Potential health benefits
36 people found this helpful
Nattokinase is an excellent blood thinner that dissolves clots in blood vessels. It supports healthy fibrinogen levels. Key benefits include reducing lymph viscosity, addressing increased blood clotting, lowering LDL cholesterol levels, and preventing coronary heart disease, strokes, and heart attacks. It also contributes to intestinal microflora normalisation and bone density, and aids skin healing. Importantly, avoid taking it with other blood thinning medications. I’ve observed improvements in my grandmother’s health—she feels better!
7.5
Supports normal blood density
1 people found this helpful
Nattokinase is an excellent blood thinner, necessary for high cholesterol and reducing the risk of stroke. I take one capsule daily to maintain normal blood density.
8
Nattokinase shows mixed cholesterol benefits
The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.
However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
7
Nattokinase affects hemostatic factors
The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects.
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.
We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.
In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
References
Liu X, Zeng X, Mahe J, Guo K, He P, et al. The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2023;15. doi:10.3390/nu15194239
Yoo HJ, Kim M, Kim M, Lee A, Jin C, et al. The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects. Food Funct. 2019;10:2888. doi:10.1039/c8fo02324g